Design, monitoring, and analysis of sequential clinical trials.


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Documentation for package ‘RCTdesign’ version 1.1

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A C D G H I M P Q R S U

RCTdesign-package Design, evaluation, monitoring, and analysis of randomized clinical trials.

-- A --

as.seqBoundary Create or test for a SeqTrial Boundary Object
as.seqDesign Group Sequential Design
as.seqScale Create a seqScale object

-- C --

changeSeqScale Change Scale for Sequential Statistics
checkSeqBoundary Check validity of a boundary object
checkSeqScale Checks if display scale is valid
confidenceInterval Confidence interval
confidenceLevel Extract group sequential design parameters from RCTdesign objects.

-- D --

dMeanSeq Distribution of Test Statistics in Group Sequential Trial
dSeq Distribution of Test Statistics in Group Sequential Trial
dZSeq Distribution of Test Statistics in Group Sequential Trial

-- G --

getDesigns Retrieve Designs and Names from RCTdesign Objects
getListNames Retrieve Designs Names from List of RCTdesign Objects

-- H --

Hexp.pcws Utility Functions for Modeling Accrual in Time to Event Analyses

-- I --

integCondSeq Distribution of Test Statistics in Group Sequential Trial
is.seqBoundary Create or test for a SeqTrial Boundary Object
is.seqDesign Group Sequential Design
is.seqScale Create a seqScale object

-- M --

meanSeq Distribution of Test Statistics in Group Sequential Trial

-- P --

plot.seqBoundary Plot a Group Sequential Design
plot.seqDesign Plot a Group Sequential Design
plot.seqInference Plot the Inference for a Group Sequential Design
plot.seqMonitor Monitoring of a Clinical Trial
plot.seqOC Computation of Operating Characteristics for a Clinical Trial Design
plot.seqOperatingChar Computation of Operating Characteristics for a Clinical Trial Design
powerTest Extract group sequential design parameters from RCTdesign objects.
print.seqBoundary Print methods for RCTdesign objects.
print.seqEvaluate Print methods for RCTdesign objects.
print.seqEvaluate Complete evaluation of a group sequential design.
print.seqHypothesis Print methods for RCTdesign objects.
print.seqInference Print methods for RCTdesign objects.
print.seqModel Print methods for RCTdesign objects.
print.seqMonitor Print methods for RCTdesign objects.
print.seqOC Print methods for RCTdesign objects.
print.seqOperatingChar Print methods for RCTdesign objects.
print.seqParameters Print methods for RCTdesign objects.
print.seqPHAccrual Print methods for RCTdesign objects.
print.seqPHNSubjects Print methods for RCTdesign objects.
print.seqScale Print methods for RCTdesign objects.
pSeq Distribution of Test Statistics in Group Sequential Trial

-- Q --

qexp.pcws Utility Functions for Modeling Accrual in Time to Event Analyses
qSeq Distribution of Test Statistics in Group Sequential Trial
qunif.pcws Utility Functions for Modeling Accrual in Time to Event Analyses

-- R --

RCTdesign Design, evaluation, monitoring, and analysis of randomized clinical trials.
RCTfunctionList List of Functions in RCTdesign
RCTversion Return Versions of all RCTdesign Functions
rexp.pcws Utility Functions for Modeling Accrual in Time to Event Analyses
rSeq Simulate Clinical Trials
rSeqBinomial Simulate Clinical Trials for the Proportions Probability Model
rSeqGeomMean Simulate Clinical Trials for the Geometric Mean Probability Model
rSeqMean Simulate Clinical Trials for the Mean Probability Model
runif.pcws Utility Functions for Modeling Accrual in Time to Event Analyses

-- S --

sampleSize Extract group sequential design parameters from RCTdesign objects.
seqBoundary Create or test for a SeqTrial Boundary Object
seqCalcAccrTime Utility Functions for Modeling Accrual in Time to Event Analyses
seqCalcATST Utility Functions for Modeling Accrual in Time to Event Analyses
seqCalcNSubj Utility Functions for Modeling Accrual in Time to Event Analyses
seqCalcSS Utility Functions for Modeling Accrual in Time to Event Analyses
seqCalcST Utility Functions for Modeling Accrual in Time to Event Analyses
seqDesign Group Sequential Design
seqDesign.boundaryShape seqDesign Boundary Shape Details
seqDesign.multiple.arms seqDesign multiple arms trials (arms>2)
seqDesign.object Group Sequential Design Object
seqDesign.probabilityModel seqDesign Probability Model Details
seqDesign.specialFamilies seqDesign Special Families
seqDesign.testSpecifications seqDesign Test Specification Details
seqEvaluate Complete evaluation of a group sequential design.
seqExtract Extract group sequential design parameters from RCTdesign objects.
seqFixDesign Create a Fixed Sample Design
seqGetDropout Utility Functions for Modeling Accrual in Time to Event Analyses
seqGetEntry Utility Functions for Modeling Accrual in Time to Event Analyses
seqGetEvent Utility Functions for Modeling Accrual in Time to Event Analyses
seqHypothesis.object Hypotheses Object
seqInference Inference for a Group Sequential Hypothesis Test
seqInference.object Inference Object
seqModel.object Group Sequential Design Model Object
seqMonitor Monitoring of a Clinical Trial
seqOC Computation of Operating Characteristics for a Clinical Trial Design
seqOC.object Operating Characteristics Object
seqOperatingChar Computation of Operating Characteristics for a Clinical Trial Design
seqOperatingChar.object Operating Characteristics Object
seqParameters.object Parameters for Group Sequential Design Object
seqPHAccrual Accrual characteristics for a hazards model design
seqPHNSubjects Accrual and followup requirements for hazards model designs
seqPHSubjects Proportional Hazards Sample Size
seqPlotASN Plot ASN and Sample Size Quantile Curves
seqPlotBoundary Plot a Group Sequential Design
seqPlotInference Plot the Inference for a Group Sequential Design
seqPlotPHNSubjects Plots of Accrual of Subjects in Hazards Probability Model
seqPlotPower Plot a Power Curve
seqPlotStopProb Stopping Probabilites
seqQuantToHazExp Utility Functions for Modeling Accrual in Time to Event Analyses
seqQuantToParWeib Utility Functions for Modeling Accrual in Time to Event Analyses
seqScale Create a seqScale object
seqScale.object Group Sequential Design Scale Object
seqScalePP Utility Functions for Modeling Accrual in Time to Event Analyses
seqSimDropout Utility Functions for Modeling Accrual in Time to Event Analyses
seqSimEntry Utility Functions for Modeling Accrual in Time to Event Analyses
seqSimEvent Utility Functions for Modeling Accrual in Time to Event Analyses

-- U --

update.seqDesign Group Sequential Design
update.seqPHAccrual Accrual characteristics for a hazards model design