Technical Reports : Frequentist Inference

 
 

Parameter estimation following group sequential hypothesis testing.

  1. Summary: A comparison of methods appropriate for statistical inference using data collected under a sequential sampling plan.

  2. Ref: Emerson SS, Fleming TR, Biometrika 77: 875-892 (1990).



Computation of the uniform minimum variance unbiased estimator of a normal mean following a group sequential test.

  1. Summary: A technical description of the computation of an unbiased estimator following a sequential test through the use of the Rao-Blackwell improvement theorem.

  2. Ref: Emerson SS, Comput Biomed Res 26: 69-73 (1993).



A computationally simpler algorithm for an unbiased estimate of a normal mean following a group sequential test.

  1. Summary: An improved method for computation of unbiased esimates following a group sequential test.

  2. Ref: Emerson SS, Kittelson JM, Biometrics 53: 365-369 (1997).



Interpretation of a leukemia clinical trial stopped early because of an observed beneficial treatment effect.

  1. Summary: A case study of inference in a setting where the stopping rule was imprecisely specified.

  2. Ref: Emerson SS, Banks PLC, Case Studies in Biometry (N. Lange, et al., eds.). New York: Wiley. pp 275-299 (1994).



Stopping a clinical trial very early based on unplanned interim analyses: A group sequential approach.

  1. Summary: A case study of inference in a setting where no stopping rule was prespecified.

  2. Ref: Emerson SS, Biometrics 51: 1152-1162 (1995).



Parameter estimation following group sequential hypothesis testing.

  1. Summary: SS Emerson Dissertation: A comparison of methods appropriate for statistical inference using data collected under a sequential sampling plan.

  2. Ref: Emerson SS, University of Washington, Department of Biostatististics (1988)