Technical Reports : Software

 
 

Statistical packages for group sequential methods.

  1. Summary: A discussion of the desirable features for sequential statistical software, and a comparison of early versions of PEST and EaSt.

  2. Ref: Emerson SS. American Statistician 50: 183-192 (1996).


S+SeqTrial: Enhanced Survival Design.

  1. Summary: A description of the models for accrual and time to event distributions used in the R package RCTdesign and the S-Plus module S+SeqTrial when calculating sample size for RCT using time to event as the primary outcome.

  2. Ref: Emerson SC, Emerson SS (2007)


S+SeqTrial: Technical overview.

  1. Summary: A technical overview of the computational methods used in the R package RCTdesign and the S-Plus module S+SeqTrial.

  2. Ref: Emerson SS, www.RCTDesign.org (2007).


 


Technical Report Topics:


  1. •Probability models

  2. •General RCT methods

  3. •Noninferiority trials

  4. •Stopping rules

  5. •Adaptive methods

  6. •Implementation

  7. •Frequentist inference

  8. •Bayesian methods

  9. •Survival outcomes

  10. •Longitudinal outcomes

  11. •Medical diagnosis

  12. •Missing data

  13. •Software